Publications

Journal articles

Aravindakshan MR, Mandal C, Pothen A, Schaller S, Maass C.
DigiLoCS: A leap forward in predictive organ-on-chip simulations.
PLOS ONE 20(1): e0314083 (2025). doi:10.1371/journal.pone.0314083
Aravindakshan MR, et al.
Parameter estimation for the oral minimal model and parameter distinctions between obese and non-obese type 2 diabetes.
DNA and Cell Biology Reports (2024). doi:10.1089/dcbr.2024.0018
Aravindakshan MR, et al.
Distinct patho-clinical clusters among uncontrolled type 2 diabetes patients: results from a prospective study in rural India.
BMJ Open Diabetes Research & Care (2022). doi:10.1136/bmjdrc-2021-002654

Aravindakshan MR, et al.under review
A closed-loop lumped parameter model for whole-body cardiovascular simulation.
Aravindakshan MR, et al.submission-ready
A comprehensive computational framework for whole-body lymphatic transport simulation.
Aravindakshan MR, et al.in preparation
A coupled cranial–spinal CSF and Circle-of-Willis lumped-parameter model: Monro–Kellie volume coupling shapes intracranial pulsatility and cerebrovascular regulation.

Aravindakshan MR, et al.
System for design of Route Control Chart (RCC) and application logic for interlocked signaling.
Indian Patent App. No. 202431029893, filed April 2024.

Lilly Deep Dive · Purdue University, IN (Mar 2026)
A whole-body digital twin for fluid transport using a 0D lumped parameter model.
10^th International Biofluid Mechanics & Mechanobiology Symposium · UC Irvine, CA (Sep 2025)
Lumped parameter model for simulating brain–body fluid dynamics.
18^th U.S. Association for Computational Mechanics · Chicago, IL (Jul 2025)
A whole-body lumped parameter model for cardiovascular simulation.
Invited · OVDF Symposium, Purdue University (Dec 2024)
Application of computational modeling towards digital twinning for human physiological systems.
Invited · University of Birmingham, UK (Dec 2023)
Digital twins for liver-on-chip devices.